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Rotenone & East Fork of Boulder Creek
#6
[quote riverdog] I have seen a lot of data in the past decade showing permethrin is neurotoxic and exposure is linked to Parkinsons....[/quote]

We're not talking about permethrin. We're talking rotenone. For some very good information concerning rotenone, it's application, and the findings of the study linking rotenone to Parkinson's, read this:

[url "http://www.fisheriessociety.org/rotenon/parkinsonstudy.shtml"]http://www.fisheriessociety.org/...parkinsonstudy.shtml[/url]

[quote "The Fish Management Chemicals Subcommittee Task Force on Fishery Chemicals of the American Fisheries Society"]
...the reported findings of a relationship between Parkinson's disease and rotenone in an Emory University study (Betarbet et al. 2000) do not suggest a need for additional precautions with respect to current uses of rotenone. Neither studies conducted for the U.S. Environmental Protection Agency nor the use of rotenone for many decades have indicated any associations with Parkinson's disease.[#ff0000] Unfortunately, the report is certain to generate unfounded fears, caused by the inaccurate and incomplete reporting of the study and its implications.[/#ff0000] In fact, Betarbet et al. (2000) concluded that their findings do not show that exposure to rotenone has caused Parkinson's disease. They stated further that "rotenone seems to have little toxicity when administered orally".[/quote]

Further, concerning the study linking Parkinsons to rotenone:

Quote:The manner that rotenone was administered to the laboratory rats was highly unnatural. Not only was it [#ff0000]administered by continuous jugular vein infusion[/#ff0000], it was mixed with DMSO and PEG. DMSO enhances tissue penetration of many chemicals (Dr. Peter Kurtz, M.D., California Department of Food and Agriculture, personal communication) The normal exposure to rotenone in humans from its use in fisheries management would be ingestion, inhalation or through the skin. Direct injection is the fastest way to deliver chemicals to the body, as evidenced in intravenous application of medicines. Continuous intravenous injection, as done in this study, also leads to continuously high levels of the chemical in the bloodstream. Normal ingestion, inhalation, and dermal exposures significantly slow down the introduction of chemicals into the bloodstream. Administering any chemical directly into living tissues can have grave consequences.


Quote:...sodium chloride (table salt) administered to developing chick embryos causes birth defects (Dr. P. Kurtz, M.D., California Department of Food and Agriculture, personal communication). However, this model has no practical predictive value for humans ingesting salt.

Rotenone is safe to use in fisheries management applications. Unfortunately, there is a lot of fear associated with it, mainly because the majority of people are not educated on the subject.
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Re: [riverdog] Rotenone & East Fork of Boulder Creek - by PBH - 09-28-2011, 08:01 PM

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